Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983162 | 0.99 | HRH3 (0.46) | HRH3MEN1KMT2AHTR4KCNH2 | |
| SCHEMBL7986311 | 0.92 | HTR4 (0.46) | HRH3KMT2AHTR4HTR7 | |
| Hydrochloric Acid SCHEMBL7982421 | 0.91 | HTR4 (0.45) | HRH3KMT2AHTR4HTR7 | |
| SCHEMBL7986053 | 0.91 | HTR7 (0.45) | HTR4KDM1AHTR7 | |
| SCHEMBL7985386 | 0.90 | HTR4 (0.42) | HTR4KDM1AHTR7 | |
| SCHEMBL7986842 | 0.90 | HRH3 (0.44) | HRH3HTR4KDM1AHTR7 | |
| Hydrochloric Acid SCHEMBL7982388 | 0.90 | HTR7 (0.44) | HTR4KDM1AHTR7 | |
| Hydrochloric Acid SCHEMBL7972035 | 0.89 | HRH3 (0.43) | HRH3HTR4KDM1AHTR7 | |
| Hydrochloric Acid SCHEMBL7972092 | 0.89 | HTR4 (0.42) | HTR4KDM1AHTR7 | |
| SCHEMBL7984555 | 0.88 | HTR7 (0.44) | HRH3MEN1KMT2AHTR4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |