SCHEMBL7981672

SCHEMBL7981672

CN(C(=O)CN1C(=O)c2ccccc2C1=O)c1ccc(C(O)Cl)cc1C(O)Cl

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
ELANE P08246 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8803622 0.86 ELANE (0.43) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL8303404 0.81 GAA (0.39) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL8801762 0.79 GAA (0.40) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL22311488 0.74 GAA (0.46) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL29472256 0.74 GAA (0.46) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL29398039 0.73 L3MBTL1 (0.63) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL7748464 0.72 LMNA (0.45) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL658515 0.71 POLB (0.42) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL10045572 0.71 POLB (0.42) POLBGAATDP1ALDH1A1KMT2A
SCHEMBL6640229 0.71 POLB (0.42) POLBGAATDP1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194396-B1 ANTIALLERGENS; ANTIINFLAMMATION AGENTS; AUTOIMMUNE DISEASE; ANTISHOCK AGENTS; ANALGESICS; E.G., A 4 OR 7-PHENYLALKYLENE-OXYBENZIMIDAZOLE UNSUBSTITUTED OR SUBSTITUTED IN THE 1,2,3-POSITION WITH AN OXY, AMINO AND/OR THIO GROUP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-02-27 US disclosed