Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741608 | 1.00 | POLB (0.46) | POLBBRD4FFAR2SLC6A2SLC6A4 | |
| SCHEMBL14049274 | 0.85 | BRD4 (0.43) | POLBBRD4FFAR2SLC6A2SLC6A4 | |
| SCHEMBL17451234 | 0.82 | POLB (0.47) | POLBBRD4FFAR2ADRB2CYP2C19 | |
| SCHEMBL8001841 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL17702817 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL12313665 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL8209874 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL8001842 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL12265956 | 0.81 | LMNA (0.56) | POLBCYP2C19CYP2C9CYP2D6MEN1 | |
| SCHEMBL16967416 | 0.78 | ADRB2 (0.52) | POLBBRD4FFAR2ADRB2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |