Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117705 | 0.82 | KDM4E (0.52) | HTR2AHRH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10513477 | 0.81 | HTR2A (0.47) | OPRM1OPRD1HTR2AHRH1KDM4E | |
| SCHEMBL13060870 | 0.81 | HTR2A (0.57) | OPRM1OPRD1HTR2AHRH1KDM4E | |
| SCHEMBL3671967 | 0.81 | OPRD1 (0.48) | OPRM1OPRD1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7632242 | 0.80 | AOC3 (0.44) | AOC3LMNASLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL11393827 | 0.80 | KDM4E (0.46) | HTR2AHRH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17847816 | 0.79 | POLB (0.40) | OPRM1OPRD1HTR2AHRH1KDM4E | |
| SCHEMBL8133703 | 0.79 | HTR2A (0.45) | OPRM1OPRD1HTR2AHRH1KDM4E | |
| SCHEMBL9513844 | 0.79 | HTR2A (0.45) | OPRM1OPRD1HTR2AHRH1KDM4E | |
| SCHEMBL9514760 | 0.79 | CARM1 (0.47) | OPRM1OPRD1HTR2AHRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |