Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796528 | 0.87 | MAPK10 (0.73) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL7341519 | 0.87 | MAPK10 (0.73) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL3279571 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL7981869 | 0.79 | KMT2A (0.55) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL22543336 | 0.76 | EGFR (0.48) | KMT2AMEN1MAPK10SMN1; SMN2L3MBTL1 | |
| SCHEMBL26186346 | 0.74 | MAPK10 (0.51) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL28130440 | 0.74 | CXCL8 (0.47) | KMT2AMEN1MAPK10SMN1; SMN2RAB9A | |
| SCHEMBL28120173 | 0.74 | MEN1 (0.58) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL221242 | 0.73 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERSMN1; SMN2 | |
| SCHEMBL29391624 | 0.73 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |