Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216481 | 0.81 | KDM4E (0.74) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL29359799 | 0.80 | KDM4E (1.00) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL4655725 | 0.80 | KDM4E (1.00) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL29433241 | 0.80 | KDM4E (1.00) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL8227395 | 0.80 | KDM4E (0.72) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL8140930 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL35129 | 0.80 | KDM4E (1.00) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL8254909 | 0.79 | NPC1 (0.69) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL17372732 | 0.79 | KDM4E (0.97) | ALDH1A1MAPTKDM4ECYP3A4MEN1 | |
| Oxcarbazepine SCHEMBL27944289 | 0.79 | KDM4E (0.97) | ALDH1A1MAPTKDM4ECYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |