Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYB5R3 | P00387 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968244 | 0.79 | PARP1 (0.62) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL7984452 | 0.72 | PARP1 (0.45) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL5670843 | 0.72 | PARP1 (0.45) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL5673003 | 0.70 | PARP1 (0.42) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL7980818 | 0.70 | PARP1 (0.46) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL7988315 | 0.70 | PARP1 (0.42) | PARP1BRD4CREBBPALOX5ALDH1A1 | |
| SCHEMBL7988038 | 0.68 | PGR (0.48) | PARP1BRD4CREBBPALDH1A1NR3C1 | |
| SCHEMBL10358538 | 0.68 | PARP1 (0.55) | PARP1BRD4CREBBPALDH1A1TP53 | |
| SCHEMBL9488687 | 0.67 | MAOA (0.37) | ALDH1A1MAPT | |
| SCHEMBL5672792 | 0.67 | BRD4 (0.41) | PARP1BRD4CREBBPALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |