Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982047 | 0.91 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4ETSHRCD274 | |
| SCHEMBL7985430 | 0.87 | MAPT (0.69) | MAPTALDH1A1KDM4ETSHRCD274 | |
| Hydrochloric Acid SCHEMBL7988692 | 0.84 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4ETSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7984637 | 0.78 | MAPT (0.64) | MAPTALDH1A1KDM4ECD274MCL1 | |
| SCHEMBL4386528 | 0.77 | LMNA (0.69) | MAPTALDH1A1KDM4ECD274MCL1 | |
| Hydrochloric Acid SCHEMBL7984565 | 0.77 | ALDH1A1 (0.76) | MAPTALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL31078467 | 0.73 | LMNA (0.55) | MAPTALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL31078333 | 0.72 | CXCR2 (0.51) | MAPTALDH1A1KDM4EMCL1KMT2A | |
| SCHEMBL2610241 | 0.72 | MCL1 (0.71) | MAPTALDH1A1KDM4ECD274MCL1 | |
| SCHEMBL7088656 | 0.71 | MCL1 (0.76) | MAPTALDH1A1KDM4ECD274MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |