SCHEMBL7982311

SCHEMBL7982311

CCNN(CC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
NR3C2 P08235 1/20 0.37
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRM1 P35372 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL28200874 0.90 KDM4E (0.50) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL9137734 0.86 GAA (0.40) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL8649205 0.83 TSHR (0.39) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL10388833 0.83 ALDH1A1 (0.42) ALDH1A1TSHRGLAMEN1KMT2A
Hydrochloric Acid SCHEMBL8619257 0.81 TSHR (0.38) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL16614019 0.81 TSHR (0.52) ALDH1A1TSHRKDM4ETDP1ALOX12
SCHEMBL5137015 0.80 CHRM5 (0.44) ALDH1A1KMT2AKDM4ESLC6A2MAPT
SCHEMBL4823355 0.79 ALDH1A1 (0.41) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL28347957 0.79 TDP1 (0.41) ALDH1A1MEN1KMT2ATDP1CHRM2
SCHEMBL8978987 0.79 ALDH1A1 (0.43) ALDH1A1TSHRGLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108264488-A A kind of preparation method for replacing phthalazone class compound 天津瑞岭化工有限公司 2018-07-10 CN claimed
CN-109796494-B A method of recycling L-fosfomycin dextrorotation phenyl ethylamine salt industrial Phosphorus From Wastewater resource and organic matter 南京道尔医药科技有限公司 2019-09-13 CN disclosed
CN-109796494-A A method of recycling L-fosfomycin dextrorotation phenyl ethylamine salt industrial Phosphorus From Wastewater resource and organic matter 南京道尔医药科技有限公司 2019-05-24 CN disclosed
CN-108264488-A A kind of preparation method for replacing phthalazone class compound 天津瑞岭化工有限公司 2018-07-10 CN disclosed
US-6235936-B1 TRANSITION METAL CATALYST FOR ARYLATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-05-22 US disclosed
EP-1058678-A2 METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES Massachusetts Institute of Technology (US) 2000-12-13 EP disclosed
WO-1999043643-A2 METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-09-02 WO disclosed
US-5672793-A NONFOULING, DISCOLORATION INHIBITION PHILLIPS PETROLEUM COMPANY (US) 1997-09-30 US disclosed
WO-1995002848-A1 MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO disclosed