Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982311 | 0.90 | ALDH1A1 (0.44) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL9137734 | 0.77 | GAA (0.40) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL9545457 | 0.77 | ALDH1A1 (0.52) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL4823355 | 0.76 | ALDH1A1 (0.41) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL8652157 | 0.76 | ALDH1A1 (0.50) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL10388833 | 0.75 | ALDH1A1 (0.42) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL8649205 | 0.75 | TSHR (0.39) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL10640116 | 0.74 | ALDH1A1 (0.40) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL9134233 | 0.74 | TDP1 (0.56) | KDM4ETDP1ALDH1A1GLATSHR | |
| SCHEMBL29137131 | 0.74 | ALDH1A1 (0.48) | KDM4ETDP1ALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |