Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309243 | 0.73 | TP53 (0.37) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL28537050 | 0.69 | TP53 (0.38) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL892937 | 0.69 | — | — | |
| SCHEMBL13686499 | 0.66 | CA12 (0.37) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL28537049 | 0.66 | ALOX15 (0.38) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL828580 | 0.65 | EGFR (0.41) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL7030037 | 0.64 | HSD17B10 (0.34) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL3730879 | 0.63 | TSHR (0.55) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL8678911 | 0.63 | CA12 (0.35) | TP53MAPTALOX15HSD17B10GABRA1 | |
| SCHEMBL5390234 | 0.63 | HDAC4 (0.46) | TP53MAPTALOX15HSD17B10GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1742015-A | Oxazolidinone and / or isoxazoline derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |