Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537050 | 0.82 | TP53 (0.38) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL29869146 | 0.77 | TP53 (0.37) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL28537049 | 0.75 | ALOX15 (0.38) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL29539724 | 0.74 | TP53 (0.35) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL7982624 | 0.73 | TP53 (0.34) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL13686499 | 0.71 | CA12 (0.37) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL1268010 | 0.71 | TP53 (0.35) | TP53MAPTALOX15HSD17B10CYP2C19 | |
| SCHEMBL6205702 | 0.68 | TP53 (0.36) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL8678911 | 0.68 | CA12 (0.35) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL5390234 | 0.68 | HDAC4 (0.46) | TP53MAPTALOX15HSD17B10NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563144-B | Compound (I) | 雅斯娜 | 2023-03-28 | — | — | CN | disclosed |