Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980544 | 0.89 | MGLL (0.41) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL24854625 | 0.81 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL6480093 | 0.77 | MGLL (0.48) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL16090103 | 0.69 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL27189028 | 0.66 | — | — | |
| SCHEMBL145760 | 0.65 | MGLL (0.56) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL7522123 | 0.64 | MGLL (0.57) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL4862588 | 0.64 | — | — | |
| SCHEMBL22904603 | 0.63 | MGLL (0.45) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL768192 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271335-B1 | HEATING A MIXTURE OF AT LEAST ONE BIS(MALEIMIDE) COMPOUND AND AT LEAST ONE MONOMERIC TRIS(FURAN) OR TETRAKIS(FURAN) COMPOUND TO FORM A GEL AND COOLING; HEATING TO A TEMPERATURE GREATER THAN 90 DEGREE C. WILL DEPOLYMERIZE THE GEL | SANDIA CORPORATION | 2001-08-07 | — | — | US | disclosed |