Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473770 | 0.91 | MAOB (0.57) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7986757 | 0.86 | EPHX2 (0.64) | EPHX2MAPK14 | |
| SCHEMBL7989749 | 0.86 | EPHX2 (0.64) | EPHX2MAPK14 | |
| SCHEMBL7986129 | 0.86 | EPHX2 (0.64) | EPHX2MAPK14 | |
| SCHEMBL7982523 | 0.85 | EPHX2 (0.65) | EPHX2MAPK14 | |
| SCHEMBL7984857 | 0.82 | EPHX2 (0.65) | EPHX2MAPK14 | |
| SCHEMBL7986234 | 0.82 | F10 (0.65) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7990811 | 0.81 | EPHX2 (0.67) | RAB9AEPHX2MAPK14 | |
| SCHEMBL3902858 | 0.81 | RAB9A (0.58) | RAB9ASMPD1 | |
| SCHEMBL7983783 | 0.81 | MAOB (0.54) | RAB9ACHRM3MAOBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |