Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.64 |
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989749 | 1.00 | EPHX2 (0.64) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7986757 | 1.00 | EPHX2 (0.64) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7982523 | 0.99 | EPHX2 (0.65) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7984857 | 0.96 | EPHX2 (0.65) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7990811 | 0.94 | EPHX2 (0.67) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7382982 | 0.90 | EPHX2 (0.58) | EPHX2PPARALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7982663 | 0.86 | RAB9A (0.58) | EPHX2MAPK14 | |
| SCHEMBL7983889 | 0.86 | MAOB (0.54) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7983783 | 0.86 | MAOB (0.54) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7982716 | 0.86 | MAOB (0.54) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |