Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992939 | 1.00 | CNR1 (0.64) | CNR1CA1ACE2KCNK3ALDH1A1 | |
| SCHEMBL22304123 | 0.93 | CNR1 (0.63) | CNR1CA1KCNK3ALDH1A1THRB | |
| SCHEMBL7981241 | 0.83 | CA2 (0.51) | CNR1CA1KCNK3ALDH1A1THRB | |
| SCHEMBL24125240 | 0.81 | CNR1 (0.51) | CNR1CA1ACE2MEN1KMT2A | |
| SCHEMBL25761064 | 0.81 | CA1 (0.55) | CNR1CA1ACE2MEN1KMT2A | |
| SCHEMBL7028999 | 0.79 | CA1 (0.57) | CA1ACE2FAAHCCR2 | |
| SCHEMBL8313862 | 0.79 | CNR1 (1.00) | CNR1KCNK3ALDH1A1THRBCNR2 | |
| SCHEMBL13963510 | 0.79 | FAAH (0.62) | CA1ACE2FAAH | |
| SCHEMBL13963508 | 0.79 | FAAH (0.62) | CA1ACE2FAAH | |
| SCHEMBL13963509 | 0.79 | FAAH (0.62) | CA1ACE2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126502-A2 | METHODS OF INHIBITING AND TREATING BIOFILMS USING GLYCOPEPTIDE ANTIBIOTICS | TARGANTA THERAPEUTICS CORP. (US) | 2009-10-15 | — | — | WO | disclosed |