Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815239 | 0.90 | MAPT (0.53) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6815249 | 0.75 | MAPT (0.47) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6814967 | 0.74 | MEN1 (0.53) | ALDH1A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL6815550 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6812750 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6814554 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6811806 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDGAAMAPTMAPK1 | |
| SCHEMBL6814533 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAMAPTRAB9A | |
| SCHEMBL31616406 | 0.72 | LMNA (0.61) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL21311334 | 0.72 | KCNK3 (0.71) | GAATSHRMAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |