Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041445 | 0.89 | CTSS (0.71) | CTSSCTSKCTSL | |
| SCHEMBL5041450 | 0.89 | CTSS (0.71) | CTSSCTSKCTSL | |
| SCHEMBL7983921 | 0.85 | EPHX2 (0.62) | PPARAEPHX2HDAC1NR1H4 | |
| SCHEMBL29527526 | 0.81 | CTSS (0.73) | CTSSCTSKPRSS1CTSL | |
| SCHEMBL7982845 | 0.81 | EPHX2 (0.52) | PPARAEPHX2HDAC1NR1H4 | |
| SCHEMBL4200549 | 0.79 | CTSS (0.73) | CTSSCTSKPRSS1CTSL | |
| SCHEMBL4200553 | 0.79 | CTSS (0.73) | CTSSCTSKPRSS1CTSL | |
| SCHEMBL7984857 | 0.79 | EPHX2 (0.65) | PPARAEPHX2HDAC1NR1H4 | |
| SCHEMBL4231742 | 0.78 | S1PR3 (0.64) | EPHX2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL7982523 | 0.77 | EPHX2 (0.65) | PPARAEPHX2HDAC1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |