Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983921 | 0.91 | EPHX2 (0.62) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7982847 | 0.81 | CTSS (0.57) | EPHX2PPARAHDAC1NR1H4 | |
| SCHEMBL7984857 | 0.80 | EPHX2 (0.65) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7982523 | 0.78 | EPHX2 (0.65) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7983917 | 0.77 | HDAC1 (0.45) | EPHX2PPARAHDAC1NR1H4NAMPT | |
| SCHEMBL7989749 | 0.77 | EPHX2 (0.64) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7986129 | 0.77 | EPHX2 (0.64) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7986757 | 0.77 | EPHX2 (0.64) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL7990811 | 0.77 | EPHX2 (0.67) | EPHX2PPARAHDAC1NR1H4LMNA | |
| SCHEMBL3274015 | 0.77 | EPHX2 (0.58) | EPHX2PPARAHDAC1NAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |