Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575961 | 0.81 | AKR1B1 (0.47) | HPRT1PARP1PARP3 | |
| SCHEMBL7575446 | 0.80 | HPRT1 (0.46) | HPRT1NOS1 | |
| SCHEMBL7570451 | 0.79 | HPRT1 (0.53) | HPRT1ALDH1A1KDM4ENOS1 | |
| SCHEMBL7567089 | 0.76 | HPRT1 (0.54) | HPRT1NOS1 | |
| SCHEMBL5250159 | 0.75 | HPRT1 (0.60) | HPRT1NOS1 | |
| SCHEMBL7574663 | 0.75 | POLB (0.47) | HPRT1ALDH1A1KDM4EPOLB | |
| SCHEMBL5258342 | 0.74 | HPRT1 (0.48) | HPRT1ALDH1A1PARP1POLB | |
| SCHEMBL7589916 | 0.74 | HPRT1 (0.52) | HPRT1NOS1 | |
| SCHEMBL7982326 | 0.74 | HPRT1 (0.51) | HPRT1ALDH1A1KDM4ENOS1 | |
| SCHEMBL7980833 | 0.73 | HPRT1 (0.45) | HPRT1ALDH1A1KDM4ETSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | claimed |
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | disclosed |