Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986801 | 0.80 | GRIN2D (0.50) | GABRA5BRD9ALDH1A1KDM4EPDE3B | |
| SCHEMBL31026820 | 0.79 | PARP1 (0.49) | ALDH1A1KDM4EGAALCKMEN1 | |
| SCHEMBL2468642 | 0.78 | DAO (0.46) | GABRA5GABRA1MAP4K4ADORA3ADORA1 | |
| SCHEMBL29235466 | 0.78 | TP53 (0.46) | GABRA5GABRA1MAP4K4CSF1RPIM1 | |
| SCHEMBL7982949 | 0.78 | GABRA5 (0.36) | GABRA5GABRA1MAP4K4POLBHTR1A | |
| SCHEMBL21755742 | 0.77 | PARP1 (0.59) | DCLK1MAP4K4CSF1RPIM1CSNK1D | |
| SCHEMBL7982902 | 0.76 | GRIN2D (0.54) | GABRA5ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL29235602 | 0.75 | PARP1 (0.45) | ALDH1A1KDM4EHPGD | |
| SCHEMBL4763948 | 0.74 | PARP1 (0.59) | GABRA5GABRA1DCLK1MAP4K4CSF1R | |
| SCHEMBL30095396 | 0.74 | PARP1 (0.59) | GABRA5GABRA1DCLK1MAP4K4CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |