Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468642 | 0.82 | DAO (0.46) | GABRA5DAOGABRA1GRIN2DGRIN3B | |
| SCHEMBL7980241 | 0.82 | DAO (0.46) | GABRA5PARP1DAOGABRA1 | |
| SCHEMBL7983014 | 0.78 | GABRA5 (0.46) | GABRA5HTR1AHTR7HTR6POLB | |
| SCHEMBL4763948 | 0.78 | PARP1 (0.59) | GABRA5PARP1POLBCHEK1CHEK2 | |
| SCHEMBL11997319 | 0.77 | IDO1 (0.40) | GABRA5PARP1CDK1GABRA1PBK | |
| SCHEMBL7969955 | 0.77 | GRIA1 (0.51) | GABRA5PARP1POLBNOS1GABRA1 | |
| Lithium Ion SCHEMBL31177616 | 0.76 | PARP1 (0.40) | GABRA5PARP1POLBCHEK1CHEK2 | |
| SCHEMBL7969712 | 0.75 | PGR (0.47) | CHEK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL31026820 | 0.74 | PARP1 (0.49) | HTR7HTR6PARP1 | |
| SCHEMBL4036186 | 0.73 | PARP1 (0.42) | GABRA5PARP1POLBCHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |