Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | SQLE | Q14534 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204638 | 0.82 | TSHR (0.41) | KDM4EMAPK1HIF1AMAPT | |
| SCHEMBL10893304 | 0.80 | EP300 (0.45) | MAPK1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL10886696 | 0.80 | EP300 (0.45) | MAPK1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL10531391 | 0.80 | EP300 (0.45) | MAPK1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL798325 | 0.79 | — | — | |
| SCHEMBL8323964 | 0.78 | KDM4E (0.60) | KDM4EMAPK1HIF1A | |
| SCHEMBL17074293 | 0.77 | ADRA1A (0.52) | CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL998029 | 0.73 | — | — | |
| SCHEMBL5754056 | 0.72 | — | — | |
| SCHEMBL9019548 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616079-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | University of Zürich (CH) | 2013-07-24 | — | — | EP | claimed |
| WO-2012034955-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | UNIVERSITY OF ZURICH (CH) | 2012-03-22 | — | — | WO | claimed |