Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7983173 | 0.91 | HPGD (0.51) | HPGDGPR119RECQLEPHX1STS | |
| SCHEMBL8018 | 0.89 | HPGD (0.58) | HPGDGPR119RECQLEPHX1KDM4E | |
| Hydrochloric Acid SCHEMBL307023 | 0.87 | HPGD (0.57) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL28357552 | 0.86 | HPGD (0.53) | HPGDGPR119RECQLEPHX1STS | |
| Acetic Acid SCHEMBL6198968 | 0.84 | HPGD (0.54) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL4171034 | 0.83 | HPGD (0.60) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL328895 | 0.83 | HPGD (0.60) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL4171032 | 0.83 | HPGD (0.60) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL4177716 | 0.81 | HPGD (0.63) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL2427502 | 0.81 | GPR119 (0.45) | HPGDGPR119RECQLEPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |