Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.56 |
| ▸ | ITGAV | P06756 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8492415 | 0.99 | ITGB3 (0.55) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7981056 | 0.91 | ITGB3 (0.47) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL7983179 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL7983192 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8492408 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8492400 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL7969576 | 0.82 | MAPK1 (0.43) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL7980904 | 0.81 | ITGB3 (0.70) | ITGB3ITGAVITGA2BITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL7983753 | 0.80 | KMT2A (0.46) | ITGB3ITGA2BKMT2AMEN1TDP1 | |
| Hydrochloric Acid SCHEMBL7982940 | 0.80 | KMT2A (0.46) | ITGB3ITGA2BKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191282-B1 | DERIVATIVES OF 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC RING IS USED AS ANTICARCINOGENIC AGENT AND ANTICOAGULANT | HOECHST MARION ROUSSEL (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5981492-A | ADMINISTERED TO THE PATIENT TO INHIBIT THROMBOCYTE AGGREGATION, THE METASTASIZATION OF CARCINOMA CELLS, THE BINDING OF OSTEOCLASTS TO THE BONE SURFACE, OR FOR THE TREATMENT OF THROMBOSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |