Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983190 | 0.87 | ITGB3 (0.52) | MAPK1HSD17B10KMT2AMEN1ITGB3 | |
| SCHEMBL7450451 | 0.85 | ITGB3 (0.56) | MAPK1HSD17B10KMT2AMEN1ITGB3 | |
| SCHEMBL7969570 | 0.85 | ITGB3 (0.56) | MAPK1HSD17B10KMT2AMEN1ITGB3 | |
| SCHEMBL7986514 | 0.85 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7982940 | 0.82 | KMT2A (0.46) | MAPK1HSD17B10KMT2AMEN1ITGB3 | |
| Hydrochloric Acid SCHEMBL7983753 | 0.82 | KMT2A (0.46) | MAPK1HSD17B10KMT2AMEN1ITGB3 | |
| SCHEMBL7983202 | 0.82 | ITGB3 (0.56) | KMT2AMEN1ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL8492415 | 0.81 | ITGB3 (0.55) | KMT2AMEN1ITGB3ITGA2BITGAV | |
| SCHEMBL7450458 | 0.80 | CRHBP (0.35) | KMT2AITGB3ITGA2BHPGDLMNA | |
| SCHEMBL7980927 | 0.76 | ITGB3 (0.54) | KMT2AMEN1ITGB3ITGA2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191282-B1 | DERIVATIVES OF 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC RING IS USED AS ANTICARCINOGENIC AGENT AND ANTICOAGULANT | HOECHST MARION ROUSSEL (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5981492-A | ADMINISTERED TO THE PATIENT TO INHIBIT THROMBOCYTE AGGREGATION, THE METASTASIZATION OF CARCINOMA CELLS, THE BINDING OF OSTEOCLASTS TO THE BONE SURFACE, OR FOR THE TREATMENT OF THROMBOSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |