Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016580 | 1.00 | ADAMTS4 (0.45) | ADAMTS4PTGS2NAMPTTBXAS1MMP1 | |
| SCHEMBL7966264 | 0.91 | PTAFR (0.44) | ADAMTS4PTGS2NAMPTHTTSMN1; SMN2 | |
| SCHEMBL7966628 | 0.91 | CA2 (0.47) | ADAMTS4NAMPTTBXAS1MMP1MMP9 | |
| SCHEMBL7966630 | 0.91 | CA2 (0.47) | ADAMTS4NAMPTTBXAS1MMP1MMP9 | |
| SCHEMBL7976863 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7980129 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7966197 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7976881 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7977066 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7978664 | 0.87 | PTAFR (0.42) | ADAMTS4POLBHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |