SCHEMBL79833

SCHEMBL79833

O=C1OC(=O)c2cc(Cl)c(Cl)cc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
AHR P35869 7/20 0.45
MAPK1 P28482 1/20 0.45
TYMS P04818 2/20 0.45
FLT1 P17948 1/20 0.43
ALDH1A1 P00352 3/20 0.40
CES1 P23141 1/20 0.39
TSHR P16473 2/20 0.39
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
THPO P40225 1/20 0.36
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL855016 0.83 TDP1 (0.39) ALOX15TDP1TYMSALDH1A1TSHR
SCHEMBL8329814 0.83 ALOX15 (0.39) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL17195980 0.83 AHR (0.36) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL11350152 0.83 GRIN2D (0.42) ALOX15TDP1TYMSALDH1A1KDM4E
SCHEMBL12292227 0.81 TYMS (0.45) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL29442905 0.81 TYMS (0.45) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL29442904 0.81 TYMS (0.45) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL32675981 0.81 TYMS (0.45) ALOX15TDP1AHRMAPK1TYMS
SCHEMBL9469304 0.81 TYMS (0.37) ALOX15TDP1TYMSALDH1A1TSHR
SCHEMBL3993249 0.81 TDP1 (0.59) ALOX15TDP1TYMSALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 961 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 CN claimed
CN-112675716-B UIO-66-NH 2 Method for preparing high-flux defect-free polyamide membrane by using base derivative 山东中莱新材料技术有限公司 2023-05-30 CN claimed
CN-112592666-B 360-DEG C-resistant high-temperature epoxy adhesive and preparation method and application thereof 康达新材料(集团)股份有限公司 2022-11-25 CN claimed
CN-112675716-A UIO-66-NH2Method for preparing high-flux defect-free polyamide membrane by using derivative 山东中莱新材料技术有限公司 2021-04-20 CN claimed
CN-112592666-A 360-DEG C-resistant high-temperature epoxy adhesive and preparation method and application thereof 上海康达化工新材料集团股份有限公司 2021-04-02 CN claimed
CN-104479081-B A kind of method by the modified polypropylene carbonate of reactive extrursion 河北工业大学 2017-03-29 CN claimed
CN-106046027-A Pyrrolo-phenothiazine-1,3-diketone containing derivative as well as preparation method and application thereof 广东工业大学 2016-10-26 CN claimed
CN-104530058-B The preparation method of octafluoro substituted phthalocyanine 天津大学 2016-09-14 CN claimed
CN-105669704-A Tetrathiafulvalene compound and synthesis method thereof 首都师范大学 2016-06-15 CN claimed
EP-0772642-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-05-14 EP claimed
EP-0719757-A1 Process for preparing 3-chlorophthalic anhydride BASF AKTIENGESELLSCHAFT (DE) 1996-07-03 EP claimed
US-5512651-A POLYESTERURETHANE COPOLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-30 US claimed
WO-1996004326-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-15 WO claimed
US-5003086-A Etherification, dehalogenation, cyclization of dihalophthalic anhydride to form monomers for polyimides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US claimed
US-4981999-A Selective removal of chlorine from chlorophthalic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1991-01-01 US claimed
EP-0398206-A1 Dioxydiphthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-22 EP claimed
US-4888403-A CURING A MIXTURE OF OLIGOESTERIFIED WOODY MATERIAL AND AN OILGOMER OF AN UNSATURATED POLYESTER OKURA KOGYO KABUSHIKI KAISHA (JP) 1989-12-19 US claimed
EP-0148366-A2 4,5-difluorophthaloyl fluoride and its preparation OCCIDENTAL CHEMICAL CORPORATION (US) 1985-07-17 EP claimed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP claimed