SCHEMBL9469304

SCHEMBL9469304

O=C1OC(=O)c2cc(Oc3cc4c(cc3Cl)C(=O)OC4=O)c(Cl)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALOX15 P16050 1/20 0.37
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31
AR P10275 1/20 0.31
NR1I2 O75469 1/20 0.31
LMNA P02545 1/20 0.31
TTR P02766 1/20 0.31
PGR P06401 1/20 0.31
HSP90AA1 P07900 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
HSPA5 P11021 1/20 0.31
HPGD P15428 1/20 0.31
CBR1 P16152 1/20 0.31
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469215 0.89 TYMS (0.32) TYMSTDP1ALOX15
SCHEMBL9638500 0.84 MAOA (0.39) TYMSTDP1ALOX15ALDH1A1MAPT
SCHEMBL79833 0.81 ALOX15 (0.48) TYMSTDP1ALOX15ALDH1A1MAPT
SCHEMBL24946580 0.74
SCHEMBL9469052 0.74 ALOX15 (0.37) TYMSTDP1ALOX15ALDH1A1
SCHEMBL8329814 0.71 ALOX15 (0.39) TYMSTDP1ALOX15ALDH1A1TSHR
SCHEMBL855016 0.71 TDP1 (0.39) TYMSTDP1ALOX15ALDH1A1TSHR
SCHEMBL11350152 0.71 GRIN2D (0.42) TYMSTDP1ALOX15ALDH1A1MAPT
SCHEMBL9743354 0.71 ALOX15 (0.34) TDP1ALOX15ALDH1A1
SCHEMBL2928543 0.70 CYP3A4 (0.53) TDP1ALOX15MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398206-A1 Dioxydiphthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-22 EP claimed
US-4943642-A POLYMER INTERMEDIATES, CURING AGENTS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-07-24 US claimed
US-5185451-A Bis-imides of dioxydiphthalic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US disclosed
US-5166404-A Dioxydiphthalic acid esters OCCIDENTAL CHEMICAL CORPORATION (US) 1992-11-24 US disclosed
US-5101006-A Polyimides and copolyimides based on halo-oxydiphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1992-03-31 US disclosed
US-5089631-A Intermediate for polyimides OCCIDENTAL CHEMICAL CORPORATION (US) 1992-02-18 US disclosed
EP-0398206-A1 Dioxydiphthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-22 EP disclosed
US-4943642-A POLYMER INTERMEDIATES, CURING AGENTS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-07-24 US disclosed