Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.52 |
| ▸ | LYN | P07948 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981896 | 0.88 | LCK (0.48) | LCKLYNBTKSRCPOLB | |
| SCHEMBL7981177 | 0.85 | LCK (0.46) | LCKLYNBTK | |
| SCHEMBL7981461 | 0.82 | LCK (0.46) | LCK | |
| SCHEMBL7983009 | 0.80 | LCK (0.53) | LCKLYNBTK | |
| SCHEMBL7969753 | 0.79 | LCK (0.51) | LCKLYNBTK | |
| SCHEMBL7983539 | 0.74 | LCK (0.53) | LCKALDH1A1MAPTHTTSRC | |
| SCHEMBL7981095 | 0.74 | LCK (0.42) | LCKLYNBTK | |
| SCHEMBL7979983 | 0.73 | LCK (0.45) | LCKLYNBTK | |
| SCHEMBL7981749 | 0.71 | LCK (0.74) | LCKLYNBTK | |
| SCHEMBL7983711 | 0.71 | LCK (0.94) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |