SCHEMBL7983533

SCHEMBL7983533

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr]C1C(C)=Cc2c(-c3ccccc3)cccc21.C[Si](C)(O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
NR1H4 Q96RI1 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ENPP3 O14638 1/20 0.31
ENPP1 P22413 1/20 0.31
HTR2B P41595 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
HNF4A P41235 1/20 0.31
NTRK1 P04629 1/20 0.30
NTRK3 Q16288 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
USP30 Q70CQ3 1/20 0.30
ALOX15 P16050 1/20 0.30
ADRA2A P08913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3404398 0.93 PDCD1 (0.35) PDCD1CD274ALDH1A1HPGDNPC1
SCHEMBL31253552 0.93 PDCD1 (0.35) PDCD1CD274ALDH1A1HPGDNPC1
SCHEMBL14905713 0.91 NPC1 (0.33) PDCD1CD274NR1H4ALDH1A1HPGD
SCHEMBL7669289 0.90 MMP1 (0.33) ALDH1A1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL7943365 0.90 PDCD1 (0.33) PDCD1CD274HNF4AUSP30CHRNB2
SCHEMBL5678404 0.88 PDCD1 (0.33) PDCD1CD274USP30CHRNB2CHRNA4
SCHEMBL7941876 0.84 NTRK1 (0.32) NR1H4ALDH1A1TSHRHTR2BTMEM97
SCHEMBL6531333 0.83 PDCD1 (0.33) PDCD1CD274
SCHEMBL7639656 0.83 NTRK1 (0.32) NR1H4ALDH1A1TSHRHTR2BTMEM97
SCHEMBL7180179 0.82 MAOB (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001051547-A1 THERMOFORMABLE ETHYLENE/STYRENE INTERPOLYMER-BASED POLYMER BLEND FILM FOR THREE-DIMENSIONAL TRANSFER FINISH FOIL DOW GLOBAL TECHNOLOGIES INC. (US) 2001-07-19 WO disclosed