Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537472 | 0.82 | HDAC3 (0.41) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL29661200 | 0.79 | CES2 (0.57) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL40389 | 0.77 | TSHR (0.54) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL29438909 | 0.77 | TSHR (0.54) | MEN1KMT2AMAPTNPC1LMNA | |
| Hydrochloric Acid SCHEMBL30994527 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| Hydrochloric Acid SCHEMBL30129608 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL8724379 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL28779162 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL27511811 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| Water SCHEMBL27470131 | 0.75 | TSHR (0.52) | MEN1KMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007416-A1 | METHOD OF PRODUCING PYRIDAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 2001-02-01 | — | — | WO | disclosed |