SCHEMBL537472

SCHEMBL537472

Cn1nc(C(F)(F)F)cc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
RAB9A P51151 4/20 0.40
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 4/20 0.40
NPC1 O15118 3/20 0.40
KMT2A Q03164 2/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25908750 0.83 KDM4E (0.34) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8932305 0.83 KDM4E (0.34) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16946322 0.83 KDM4E (0.34) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7983655 0.82 MEN1 (0.42) RAB9AALDH1A1NPC1KMT2ALMNA
SCHEMBL8932286 0.80 KDM4E (0.55) KDM4ELMNAGRNSORT1
SCHEMBL28502037 0.78 KDM4E (0.40) KDM4ELMNAGRNSORT1
SCHEMBL16487838 0.77 PTGS1 (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2611106 0.76 PKM (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL365942 0.76 RAB9A (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL938217 0.76 RAB9A (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850178-B Preparation method of 1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 宁夏格瑞精细化工有限公司 2025-04-04 CN claimed
CN-119504590-A 1-Methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole and preparation method thereof 鹤壁市宝瑞德化工有限公司 2025-02-25 CN claimed
WO-2024209278-A1 A PROCESS FOR THE PREPARATION OF PYROXASULFONE GHARDA CHEMICALS LIMITED (IN) 2024-10-10 WO claimed
CN-118255757-B Continuous synthesis method of pyribenzoxim 吉林凯莱英医药化学有限公司 2024-09-27 CN claimed
CN-118255757-A Continuous synthesis method of pyribenzoxim 吉林凯莱英医药化学有限公司 2024-06-28 CN claimed
CN-118221663-A Continuous synthesis method of pyribenzoxim 吉林凯莱英医药化学有限公司 2024-06-21 CN claimed
CN-117924265-B Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-06-18 CN claimed
CN-117924265-A Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-04-26 CN claimed
CN-117777122-A Synthesis method of pyrifos 山东润博生物科技有限公司 2024-03-29 CN claimed
CN-114716428-B Method for preparing metazopyr intermediate 山东潍坊润丰化工股份有限公司 2024-02-06 CN claimed
CN-115850178-A Preparation method of 1-methyl-3- (trifluoromethyl) -1H-pyrazole-5-alcohol 宁夏格瑞精细化工有限公司 2023-03-28 CN claimed
CN-113754647-B Synthesis method of sulfuryl pyraflufen-ethyl and intermediate thereof 山东润博生物科技有限公司 2023-02-17 CN claimed
CN-113754648-B Preparation method of xaflufen and intermediate thereof 山东润博生物科技有限公司 2023-02-17 CN claimed
CN-114716428-A Method for preparing sulpyrazoxazole intermediate 山东潍坊润丰化工股份有限公司 2022-07-08 CN claimed
CN-113979944-A Synthesis method of high-selectivity 1-methyl-3- (trifluoromethyl) -1H-pyrazole-5-alcohol 杭州欧晨科技有限公司 2022-01-28 CN claimed
CN-113831333-A Synthetic method of sulfuryl pyraflufen 大连九信精细化工有限公司 2021-12-24 CN claimed
CN-113754647-A Synthesis method of sulfuryl pyraflufen-ethyl and intermediate thereof 山东润博生物科技有限公司 2021-12-07 CN claimed
CN-113754648-A Preparation method of xaflufen and intermediate thereof 山东润博生物科技有限公司 2021-12-07 CN claimed
WO-2020240392-A1 PROCESS FOR PREPARATION OF PYROXASULFONE PI INDUSTRIES LIMITED (IN) 2020-12-03 WO claimed
CN-110330458-A Aryloxyacetic acid class HPPD inhibitor or its salt, herbicidal composition, preparation method and purposes 中国药科大学 2019-10-15 CN claimed