Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466529 | 0.87 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7981628 | 0.86 | CHRM4 (0.53) | MEN1KMT2AMCHR1DRD4 | |
| SCHEMBL3052457 | 0.85 | HDAC3 (0.59) | DRD4 | |
| SCHEMBL803459 | 0.84 | ACHE (0.67) | — | |
| SCHEMBL14432029 | 0.83 | DRD2 (0.56) | DRD4 | |
| SCHEMBL3289146 | 0.83 | DRD2 (0.56) | DRD4 | |
| SCHEMBL5450728 | 0.83 | DRD2 (0.56) | DRD4 | |
| SCHEMBL4852114 | 0.83 | SLC6A2 (0.63) | CCR3LMNA | |
| SCHEMBL30049396 | 0.82 | ACHE (0.58) | — | |
| Methylamine SCHEMBL5634043 | 0.81 | DRD2 (0.55) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |