Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.55 |
| ▸ | PRKACA | P17612 | 7/20 | 0.42 |
| ▸ | PRKACG | P22612 | 7/20 | 0.42 |
| ▸ | PRKACB | P22694 | 7/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969684 | 0.71 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL3882600 | 0.69 | SRC (0.45) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL15218462 | 0.67 | TSPO (0.40) | NPY5R | |
| SCHEMBL29384353 | 0.59 | SRC (0.53) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL29393709 | 0.59 | SRC (0.53) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL212835 | 0.59 | SRC (0.53) | SRCPRKACAPRKACGPRKACB | |
| Acetone SCHEMBL15739074 | 0.59 | HPGD (0.43) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL3077415 | 0.59 | SRC (0.37) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL3878145 | 0.58 | SRC (0.50) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL15680200 | 0.57 | SRC (0.48) | SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |