Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998166 | 0.89 | STING1 (0.38) | MEN1KMT2ASTING1KDM4EL3MBTL1 | |
| SCHEMBL7983679 | 0.83 | HPGD (0.40) | MEN1KMT2ASTING1KDM4EL3MBTL1 | |
| SCHEMBL7997825 | 0.82 | STING1 (0.47) | STING1L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL7984304 | 0.81 | STING1 (0.49) | STING1L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL7983932 | 0.80 | STING1 (0.42) | MEN1KMT2ASTING1KDM4EL3MBTL1 | |
| SCHEMBL7995372 | 0.78 | STING1 (0.42) | MEN1KMT2ASTING1L3MBTL1 | |
| SCHEMBL7998407 | 0.77 | STING1 (0.41) | STING1L3MBTL1 | |
| SCHEMBL7983874 | 0.77 | STING1 (0.43) | STING1KDM4EL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7994269 | 0.77 | STING1 (0.41) | MEN1KMT2ASTING1KDM4EL3MBTL1 | |
| SCHEMBL7995743 | 0.76 | STING1 (0.41) | MEN1KMT2ASTING1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |