Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998424 | 0.85 | STING1 (0.45) | STING1PPARGMAPTSMN1; SMN2LMNA | |
| SCHEMBL7997825 | 0.83 | STING1 (0.47) | STING1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7984304 | 0.82 | STING1 (0.49) | STING1MAPTALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7995372 | 0.81 | STING1 (0.42) | STING1L3MBTL1 | |
| SCHEMBL7984211 | 0.80 | STING1 (0.43) | STING1L3MBTL1 | |
| SCHEMBL7998407 | 0.80 | STING1 (0.41) | STING1MAPTL3MBTL1 | |
| SCHEMBL7983932 | 0.80 | STING1 (0.42) | STING1KDM4EIDO1L3MBTL1 | |
| SCHEMBL7995743 | 0.79 | STING1 (0.41) | STING1L3MBTL1 | |
| SCHEMBL7994572 | 0.79 | NTRK1 (0.40) | STING1SMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL7994841 | 0.79 | LMNA (0.40) | STING1SMN1; SMN2LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |