Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994572 | 0.88 | NTRK1 (0.40) | HPGDLMNASMN1; SMN2STING1TP53 | |
| SCHEMBL7994841 | 0.87 | LMNA (0.40) | HPGDLMNASMN1; SMN2STING1TP53 | |
| SCHEMBL7983833 | 0.83 | MEN1 (0.41) | SMN1; SMN2STING1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7998166 | 0.79 | STING1 (0.38) | SMN1; SMN2STING1L3MBTL1KDM4EMEN1 | |
| SCHEMBL7984211 | 0.79 | STING1 (0.43) | STING1L3MBTL1 | |
| SCHEMBL7997825 | 0.75 | STING1 (0.47) | STING1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7984304 | 0.74 | STING1 (0.49) | STING1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7983874 | 0.74 | STING1 (0.43) | LMNASMN1; SMN2STING1MAPTNPC1 | |
| SCHEMBL7995372 | 0.74 | STING1 (0.42) | STING1L3MBTL1MEN1KMT2A | |
| SCHEMBL7983932 | 0.74 | STING1 (0.42) | STING1POLBL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |