Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983873 | 0.99 | HDAC1 (0.41) | HDAC1HDAC8HDAC6LMNATP53 | |
| SCHEMBL7983124 | 0.87 | HDAC3 (0.51) | HDAC1HDAC8HDAC6ACHEDRD4 | |
| Hydrochloric Acid SCHEMBL7983228 | 0.86 | HDAC3 (0.50) | HDAC1HDAC8HDAC6ACHEDRD4 | |
| SCHEMBL7989656 | 0.86 | MCHR1 (0.44) | HDAC1HDAC8HDAC6LMNATP53 | |
| Hydrochloric Acid SCHEMBL7981956 | 0.85 | MCHR1 (0.43) | HDAC1HDAC8HDAC6LMNATP53 | |
| SCHEMBL7971774 | 0.85 | MCHR1 (0.41) | HDAC1HDAC8HDAC6LMNATP53 | |
| SCHEMBL7986626 | 0.85 | LMNA (0.38) | HDAC1HDAC8HDAC6LMNATP53 | |
| Hydrochloric Acid SCHEMBL7982672 | 0.85 | MCHR1 (0.41) | HDAC1HDAC8HDAC6LMNATP53 | |
| Hydrochloric Acid SCHEMBL7982968 | 0.84 | LMNA (0.38) | HDAC1HDAC8HDAC6LMNATP53 | |
| SCHEMBL7971613 | 0.83 | KMT2A (0.41) | ACHEHTR2AHTR2COPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |