Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982520 | 0.99 | KMT2A (0.40) | KMT2AGSK3BACHEMEN1CACNA1G | |
| SCHEMBL7971786 | 0.95 | KMT2A (0.40) | KMT2AGSK3BACHEMEN1POLB | |
| Hydrochloric Acid SCHEMBL7985629 | 0.94 | KMT2A (0.39) | KMT2AGSK3BACHEMEN1POLB | |
| SCHEMBL7971862 | 0.90 | TP53 (0.40) | GSK3B | |
| Hydrochloric Acid SCHEMBL7982031 | 0.89 | TP53 (0.39) | HTR2AHTR4 | |
| SCHEMBL7981833 | 0.88 | HTR4 (0.47) | GSK3BACHEHTR2AHTR4 | |
| SCHEMBL7982581 | 0.88 | CCR3 (0.46) | GSK3BCCR3HTR2AHTR4HTR2C | |
| Hydrochloric Acid SCHEMBL7986403 | 0.87 | HTR4 (0.47) | GSK3BACHEHTR2AHTR4 | |
| SCHEMBL7971626 | 0.87 | HTR7 (0.44) | GSK3B | |
| Hydrochloric Acid SCHEMBL7983273 | 0.87 | CCR3 (0.45) | GSK3BCCR3HTR2AHTR4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |