Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477203 | 0.92 | MAOB (0.55) | MAOBPTGDR2KDM4EALDH1A1POLB | |
| SCHEMBL7970032 | 0.87 | CYP19A1 (0.57) | MAOBPTGDR2KDM4EALDH1A1POLB | |
| SCHEMBL7970467 | 0.81 | CYP19A1 (0.41) | MAOBPTGDR2GSTP1PTGER1PDCD1 | |
| SCHEMBL6554874 | 0.81 | MAOB (0.55) | MAOBPTGDR2KDM4EALDH1A1POLB | |
| SCHEMBL7982330 | 0.80 | APP (0.48) | GSTP1 | |
| SCHEMBL2570360 | 0.79 | CYP19A1 (0.62) | MAOBPTGDR2GSTP1PTGER1PDCD1 | |
| SCHEMBL2985019 | 0.78 | CARM1 (0.55) | KDM4EALDH1A1HPGDGSTP1PTGER1 | |
| SCHEMBL6477064 | 0.78 | MAOB (0.55) | MAOBPTGER1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6490398 | 0.78 | MAOB (0.55) | MAOBALDH1A1PTGER1PDCD1CD274 | |
| SCHEMBL3501181 | 0.77 | FNTA (0.60) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297239-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2001-10-02 | — | — | US | disclosed |