Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853160 | 0.91 | APP (0.49) | APPELANEF2FFAR1 | |
| SCHEMBL2985019 | 0.82 | CARM1 (0.55) | GSTP1RXRARXRBRXRGFFAR1 | |
| SCHEMBL7983941 | 0.80 | MAOB (0.47) | GSTP1 | |
| SCHEMBL1023923 | 0.79 | ELANE (0.53) | APPELANEF2FFAR1 | |
| SCHEMBL18906416 | 0.79 | ELANE (0.49) | ELANEF2 | |
| SCHEMBL11847148 | 0.77 | APP (0.47) | APPFFAR1 | |
| SCHEMBL3739211 | 0.77 | CYP11B1 (0.41) | IDO1 | |
| SCHEMBL4698492 | 0.76 | TSHR (0.48) | ELANEF2 | |
| SCHEMBL7907404 | 0.74 | ALOX5 (0.54) | GSTP1ELANEF2 | |
| SCHEMBL7984303 | 0.74 | FFAR1 (0.46) | APPGSTP1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297239-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2001-10-02 | — | — | US | disclosed |