Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981126 | 0.87 | ADORA2A (0.36) | ADORA2AADORA1TLR7HDAC6HDAC4 | |
| SCHEMBL7967624 | 0.83 | KDM4E (0.46) | ADORA2AADORA1TLR7KDM4EALDH1A1 | |
| SCHEMBL10918545 | 0.80 | HDAC6 (0.47) | HDAC6HDAC4HDAC1 | |
| SCHEMBL7968276 | 0.78 | BLM (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL30047582 | 0.77 | KDM4E (0.37) | ADORA2AADORA1TLR7HDAC6HDAC4 | |
| SCHEMBL3155510 | 0.75 | KDM4E (0.58) | ADORA2AADORA1TLR7HDAC6HDAC4 | |
| SCHEMBL7981421 | 0.74 | KDM4E (0.47) | ADORA2AADORA1TLR7KDM4EALDH1A1 | |
| SCHEMBL4846999 | 0.73 | ADORA2A (0.42) | ADORA2AADORA1TLR7ALDH1A1 | |
| SCHEMBL8058952 | 0.72 | ADORA2B (0.40) | ADORA2AADORA1DPP4ALDH1A1 | |
| SCHEMBL9391801 | 0.72 | CSNK2A2 (0.44) | ADORA2AADORA1HDAC6HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001094348-A1 | ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2001-12-13 | — | — | WO | disclosed |