SCHEMBL7983997

SCHEMBL7983997

CCCCCc1cccoc1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.44
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
PPARA Q07869 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
PPARG P37231 2/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SAE1 Q9UBE0 1/20 0.41
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
MAPT P10636 1/20 0.40
GPR84 Q9NQS5 1/20 0.39
CTRC Q99895 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776421 0.98 LIPG (0.47) LIPGNR1H2NR1H3BIDMCL1
Bromide SCHEMBL29257750 0.96 LIPG (0.46) LIPGNR1H2NR1H3BIDMCL1
SCHEMBL28413724 0.94 CTRC (0.43) LIPGNR1H2NR1H3BIDMCL1
SCHEMBL29194801 0.92 LIPG (0.42) LIPGNR1H2NR1H3BIDMCL1
SCHEMBL10425151 0.86 ELANE (0.39) MAPTALDH1A1POLBHTTL3MBTL1
SCHEMBL981305 0.80
SCHEMBL30195050 0.76 SMN1; SMN2 (0.42) BIDMCL1BCL2L1BAK1MAPT
SCHEMBL4054834 0.76 SRC (0.39) LIPGNR1H2NR1H3MAPTCTRC
SCHEMBL16823391 0.73 CA1 (0.44) MAPTCTRCALDH1A1POLBHTT
SCHEMBL11912452 0.73 LIPG (0.47) LIPGNR1H2NR1H3BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4117451-A1 PROCESS FOR PRODUCING AN AROMA-LADEN GAS, AROMA-LADEN GAS AND USE OF THE AROMA-LADEN GAS Döhler GmbH (DE) 2023-01-18 EP claimed
CN-109535174-A A kind of two sulphur pyrrolones of N- aryl-pyranone hybrid derivatives and its preparation method and application 桂林医学院 2019-03-29 CN claimed
EP-4243619-A1 CITRUS OIL EXTRACT Firmenich SA (CH) 2023-09-20 EP disclosed
WO-2022101424-A1 CITRUS OIL EXTRACT FIRMENICH SA (CH) 2022-05-19 WO disclosed
US-20210340121-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-11-04 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
US-11008302-B2 Substituted pyridine and pyrimidines and their use as GluN2B receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2021-05-18 US disclosed
CN-112481326-A Method for producing 6-pentyl-2H-pyran-2-one by virtue of loss fermentation 宜宾五粮液股份有限公司 2021-03-12 CN disclosed
EP-3774732-A2 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2021-02-17 EP disclosed
US-20190308950-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-10-10 US disclosed
WO-2019193516-A2 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-10-10 WO disclosed
CN-109535174-A A kind of two sulphur pyrrolones of N- aryl-pyranone hybrid derivatives and its preparation method and application 桂林医学院 2019-03-29 CN disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
US-9959392-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-05-01 US disclosed
US-20140221269-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-08-07 US disclosed
EP-2735607-A1 Strain of Trichoderma harzianum and controlled release composition which contains said strain SC Corx Bioneer Ceu SA (RO) 2014-05-28 EP disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
WO-2001051481-A1 METHOD FOR THE SYNTHESIS OF 6N-PENTYL-2H-PYRAN-2-ONE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2001-07-19 WO disclosed
EP-0588137-B1 3-Aryl-2-pyranone derivatives BAYER AG (DE) 1999-02-03 EP disclosed
EP-0588137-A1 3-Aryl-2-pyranone derivatives BAYER AG (DE) 1994-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190308950-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS GRIN2B, GRIN2A, GRIN3B LIPG 4764/4885NR1H2 557/4885NR1H3 671/4885
US-20210340121-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS GRIN2B, GRIN2A, GRIN3B LIPG 4764/4885NR1H2 557/4885NR1H3 671/4885
US-11008302-B2 Substituted pyridine and pyrimidines and their use as GluN2B receptor modulators GRIN2B, GRIN2A, GRIN3B LIPG 4785/4885NR1H2 499/4885NR1H3 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.