Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 11/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984011 | 1.00 | CCR5 (0.43) | CCR5KDM1AHRH3TACR1TLR2 | |
| SCHEMBL7987321 | 0.90 | CCR5 (0.40) | CCR5KDM1AHRH3TACR1TLR2 | |
| SCHEMBL7987333 | 0.90 | CCR5 (0.40) | CCR5KDM1AHRH3TACR1TLR2 | |
| SCHEMBL7982898 | 0.83 | CCR5 (0.46) | CCR5 | |
| SCHEMBL7982904 | 0.83 | CCR5 (0.46) | CCR5 | |
| SCHEMBL7657419 | 0.81 | CCR5 (0.46) | CCR5 | |
| SCHEMBL7665731 | 0.81 | CCR5 (0.46) | CCR5 | |
| SCHEMBL7657434 | 0.81 | CCR5 (0.46) | CCR5 | |
| SCHEMBL7653015 | 0.80 | CCR5 (0.48) | CCR5 | |
| SCHEMBL7652217 | 0.80 | CCR5 (0.48) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |