Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.47 |
| ▸ | HTR3B | O95264 | 6/20 | 0.47 |
| ▸ | HTR3A | P46098 | 6/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7122972 | 0.99 | HTR3E (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7125602 | 0.78 | TTK (0.39) | PRMT5WDR77DYRK1AGSK3BWNT1 | |
| SCHEMBL6754326 | 0.76 | MAP4K4 (0.49) | PRMT5WDR77CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6756716 | 0.76 | FYN (0.54) | DYRK1AGSK3B | |
| SCHEMBL7122138 | 0.75 | NPFFR1 (0.39) | DYRK1AGSK3BWNT1 | |
| SCHEMBL7117412 | 0.74 | DYRK1A (0.39) | MAPTDYRK1AGSK3BWNT1 | |
| SCHEMBL7128738 | 0.73 | MAPT (0.51) | PRMT5WDR77CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7984129 | 0.73 | FGFR3 (0.42) | DYRK1AGSK3BWNT1 | |
| SCHEMBL7121296 | 0.73 | CYP1A2 (0.50) | CYP1A2DYRK1AGSK3BWNT1 | |
| Hydrochloric Acid SCHEMBL7123999 | 0.72 | FGFR3 (0.41) | DYRK1AGSK3BWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |