SCHEMBL7984151

SCHEMBL7984151

Nc1nc2ncn(CCC(CO)CO)c2c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
VCP P55072 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
TK1 P04183 2/20 0.46
PNP P00491 4/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HPRT1 P00492 11/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7968276 0.88 BLM (0.42) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL48362 0.85 TK1 (0.51) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL29286377 0.85 TK1 (0.46) BLMMEN1ALDH1A1KMT2ATK1
SCHEMBL1665132 0.82 TK1 (0.47) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL7977785 0.82 TK1 (0.64) BLMTK1PNPUSP2TSHR
SCHEMBL4322052 0.81 HPRT1 (0.42) BLMMEN1ALDH1A1LMNACYP3A4
Penciclovir SCHEMBL3495 0.81 TK1 (0.70) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL20472317 0.81 SMN1; SMN2 (0.45) BLMMEN1ALDH1A1LMNACYP3A4
SCHEMBL48223 0.80 PNP (0.42) BLMMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL27710751 0.80 ADORA2A (0.52) MEN1ALDH1A1KMT2ATK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001094348-A1 ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-12-13 WO disclosed