Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968925 | 0.80 | CYP19A1 (0.82) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL10532352 | 0.74 | CYP19A1 (1.00) | CYP19A1BACE1BACE2 | |
| SCHEMBL10532398 | 0.71 | CYP19A1 (0.70) | CYP19A1ALDH1A1KMT2AMEN1BACE1 | |
| SCHEMBL8969269 | 0.67 | CYP19A1 (0.62) | CYP19A1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10381119 | 0.66 | CYP19A1 (0.82) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL7386254 | 0.62 | ALDH1A1 (0.56) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL20274598 | 0.62 | CYP19A1 (0.47) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL16724579 | 0.62 | CYP19A1 (0.47) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL7386256 | 0.62 | ALDH1A1 (0.56) | CYP19A1ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL9524373 | 0.61 | ELANE (0.56) | CYP19A1ALDH1A1ELANEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |