Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968925 | 0.85 | CYP19A1 (0.82) | CYP19A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11081758 | 0.77 | CYP19A1 (0.76) | CYP19A1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL10532352 | 0.77 | CYP19A1 (1.00) | CYP19A1BACE1BACE2 | |
| SCHEMBL11078445 | 0.75 | CYP19A1 (0.71) | CYP19A1ALDH1A1SMN1; SMN2BACE1BACE2 | |
| SCHEMBL11085254 | 0.75 | CYP19A1 (0.51) | CYP19A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9410346 | 0.74 | CYP19A1 (0.64) | CYP19A1ALDH1A1SMN1; SMN2HSD17B10MAPK1 | |
| SCHEMBL10532398 | 0.73 | CYP19A1 (0.70) | CYP19A1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11079959 | 0.72 | CYP19A1 (0.74) | CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11463156 | 0.71 | CYP19A1 (0.48) | CYP19A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10529975 | 0.69 | CYP19A1 (1.00) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600507-B1 | 3-Azabicyclo(3.1.0.)hexane-2-one derivatives and Herbicidal Compositions Containing them as Herbicidally Active Ingredients | MITSUI TOATSU CHEMICALS (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5352655-A | Pre- and postemergence; rice | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0600507-A1 | 3-Azabicyclo(3.1.0.)hexane-2-one derivatives and Herbicidal Compositions Containing them as Herbicidally Active Ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-4435419-A | Method of treating depression using azabicyclohexanes | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| US-4231935-A | ANXIOLYTICS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4196120-A | 1,2-BIS(HYDROCARBYLSULFONYLOXY OR HALO METHYL)CYCLOPROPYLBENZENE, OPTICAL ACITIVITY ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4131611-A | ANXIOLYTIC, ANALGESIC | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |