Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994379 | 0.94 | PABPC1 (0.38) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL17179171 | 0.81 | HTT (0.41) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL30134360 | 0.80 | PDE10A (0.41) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL23093834 | 0.78 | PDE10A (0.40) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL30192121 | 0.78 | PABPC1 (0.41) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9968617 | 0.78 | PDE10A (0.62) | PDE10ACYP1A2ALDH1A1MEN1MAPT | |
| SCHEMBL23093846 | 0.75 | PDE10A (0.46) | PDE10AHTTCYP1A2CYP2C19PABPC1 | |
| SCHEMBL26919701 | 0.75 | HTT (0.44) | HTTCYP1A2CYP2C19ALDH1A1PABPC1 | |
| SCHEMBL13226945 | 0.75 | PABPC1 (0.41) | PDE10AHTTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL28524079 | 0.73 | AURKA (0.41) | PDE10AHTTALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |